Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Inhbe/Inhbctm1Sjl
Name:	inhibin beta-C; targeted mutation 1, Sejin Lee
MGI ID:	MGI:5319699
Gene:	Inhbc  Location: Chr10:127192191-127206300 bp, - strand  Genetic Position: Chr10, 74.5 cM
Alliance:	Inhbe/Inhbctm1Sjl page

Germline Transmission:	Earliest citation of germline transmission: J:182827
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion   Mutation details: The exon encoding the C terminal domain of Inhbe and all of the coding sequence of Inhbc were replaced with a neo cassette via homologous recombination. (J:182827)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Inhbc Mutation:	46 strains or lines available

Original:	J:182827 Lee SJ, et al., Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008
All:	1 reference(s)