Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc6a3tm1.1Asor
Name:	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; targeted mutation 1.1, Alexander Sorkin
MGI ID:	MGI:5319237
Synonyms:	DATHA
Gene:	Slc6a3  Location: Chr13:73684866-73726791 bp, + strand  Genetic Position: Chr13, 40.1 cM
Alliance:	Slc6a3tm1.1Asor page

Germline Transmission:	Earliest citation of germline transmission: J:183289
Parent Cell Line:	EC7.1 (ES Cell)
Strain of Origin:	(C57BL/6J x 129X1/SvJ)F1

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted downstream of exon 3. Exon 4 was replaced with one with a human influenza hemagglutinin (HA) tag at the 5' end of the exon. Cre-mediated recombination removed the neo cassette. Western blot analysis confirmed normal protein expression levels. (J:183289)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc6a3 Mutation:	66 strains or lines available

Original:	J:183289 Rao A, et al., Epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. FASEB J. 2012 May;26(5):1921-33
All:	3 reference(s)