Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tph2tm1Mscl
Name:	tryptophan hydroxylase 2; targeted mutation 1, Michael S Clark
MGI ID:	MGI:5318587
Synonyms:	Tph2lox
Gene:	Tph2  Location: Chr10:114914546-115020927 bp, - strand  Genetic Position: Chr10, 63.51 cM
Alliance:	Tph2tm1Mscl page

Germline Transmission:	Earliest citation of germline transmission: J:182577
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     The first exon was flanked with loxP sites. (J:182577)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tph2 Mutation:	41 strains or lines available

Original:	J:182577 Wu Q, et al., Deciphering a neuronal circuit that mediates appetite. Nature. 2012 Mar 29;483(7391):594-7
All:	4 reference(s)