Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Epcamtm1.1Mcu
Name:	epithelial cell adhesion molecule; targeted mutation 1.1, Mark C Udey
MGI ID:	MGI:5318399
Synonyms:	EpCAMfl
Gene:	Epcam  Location: Chr17:87943407-87958555 bp, + strand  Genetic Position: Chr17, 57.87 cM
Alliance:	Epcamtm1.1Mcu page

Germline Transmission:	Earliest citation of germline transmission: J:182665
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	(C57BL/6 x 129)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted 200 bp upstream of exon 1 and a floxed and FRT flanked neo cassette was inserted 600 bp downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:182665)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epcam Mutation:	33 strains or lines available

Original:	J:182665 Gaiser MR, et al., Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E889-97
All:	3 reference(s)