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Maftm2.1Cbm
Targeted Allele Detail
Summary
Symbol: Maftm2.1Cbm
Name: MAF bZIP transcription factor; targeted mutation 2.1, Carmen Birchmeier
MGI ID: MGI:5316775
Synonyms: c-Mafflox
Gene: Maf  Location: Chr8:116429992-116433633 bp, - strand  Genetic Position: Chr8, 62.61 cM
Alliance: Maftm2.1Cbm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181639
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of the open reading frame. Flp-mediated recombination removed the neo cassette. (J:181639)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Maf Mutation:  26 strains or lines available
References
Original:  J:181639 Wende H, et al., The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory