Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mir7-2tm1Mtm
Name:	microRNA 7-2; targeted mutation 1, Michael McManus
MGI ID:	MGI:5314250
Gene:	Mir7-2  Location: Chr7:78538025-78538121 bp, + strand  Genetic Position: Chr7, 44.83 cM
Alliance:	Mir7-2tm1Mtm page

Germline Transmission:	Earliest citation of germline transmission: J:181752
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop. (J:181752)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir7-2 Mutation:	3 strains or lines available

Original:	J:181752 Park CY, et al., A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012;1(4):385-91
All:	2 reference(s)