Fbn1tm3.1Lysa
Targeted Allele Detail
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| Symbol: |
Fbn1tm3.1Lysa |
| Name: |
fibrillin 1; targeted mutation 3.1, Lynn Y Sakai |
| MGI ID: |
MGI:5313326 |
| Synonyms: |
Fbn1floxed WMdelta |
| Gene: |
Fbn1 Location: Chr2:125142514-125348417 bp, - strand Genetic Position: Chr2, 61.38 cM, cytoband F
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| Alliance: |
Fbn1tm3.1Lysa page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:181493
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 10. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 10. An additional loxP site was inserted downstream of exon 12. Flp-mediated recombination removed the neo cassette leaving exons 10 and 11 floxed.
(J:181493)
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Generation of the Fbn1tm3.1Lysa and Fbn1tm3.2Lysa alleles |
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Fbn1 Mutation: |
171 strains or lines available
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| Original: |
J:181493 Sengle G, et al., Microenvironmental regulation by fibrillin-1. PLoS Genet. 2012 Jan;8(1):e1002425 |
| All: |
1 reference(s) |
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Analysis Tools
