Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vldlrtm1Lex
Name:	very low density lipoprotein receptor; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:5312686
Gene:	Vldlr  Location: Chr19:27193884-27231631 bp, + strand  Genetic Position: Chr19, 21.77 cM
Alliance:	Vldlrtm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:181399
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Exons 4 and 5 were replaced with a beta-geo/Puro cassette. (J:181399)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vldlr Mutation:	69 strains or lines available

Original:	J:181399 Paes KT, et al., Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6452-61
All:	1 reference(s)