Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mir34atm1.1Lhe
Name:	microRNA 34a; targeted mutation 1.1, Lin He
MGI ID:	MGI:5308792
Synonyms:	Mir34atm1.1Ghan
Gene:	Mir34a  Location: Chr4:150152911-150153012 bp, + strand  Genetic Position: Chr4, 80.85 cM
Alliance:	Mir34atm1.1Lhe page

Germline Transmission:	Earliest citation of germline transmission: J:180692
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion   Mutation details: The microRNA was replaced with a lacZ gene and neo cassette flanked by neo and FRT sites. Flp-mediated recombination removed the neo cassette. Real-time PCR confirmed the absence of transcript expression in mouse embryonic fibroblasts. (J:180692)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir34a Mutation:	9 strains or lines available

Original:	J:180692 Choi YJ, et al., miR-34 miRNAs provide a barrier for somatic cell reprogramming. Nat Cell Biol. 2011 Nov;13(11):1353-60
All:	6 reference(s)