Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm11Sia
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Shinichi Aizawa
MGI ID:	MGI:5308584
Synonyms:	Gt(ROSA)26Sortm11(Igk/PDGFRB/KikGR1)Sia, R26R-Display-Kikume Green-Red
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm11Sia page

Germline Transmission:	Earliest citation of germline transmission: J:180918
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette and membrane-specific murine Igk leader sequence and human PDGFRB transmembrane domain (from pDisplay) fused to the Kikume Green-Red (KikGR1) reporter, was inserted into the locus. (J:180918)

Conditional targeting of the ROSA26 locus to generate various reporter lines

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:180918 Abe T, et al., Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging. Genesis. 2011 Jul;49(7):579-90
All:	1 reference(s)