Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm4.1Sia
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 4.1, Shinichi Aizawa
MGI ID:	MGI:5308561
Synonyms:	Gt(ROSA)26Sortm4.1(HIST1H2BB/mKeima-Red)Sia, R26-H2B-mKeima-Red
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm4.1Sia page

Germline Transmission:	Earliest citation of germline transmission: J:180918
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette and the C-terminus of the nuclear human histone H2B fused to the mKeima-Red reporter, was inserted into the locus. Cre-mediated recombination removed the neo cassette. (J:180918)

Conditional targeting of the ROSA26 locus to generate various reporter lines

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:180918 Abe T, et al., Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging. Genesis. 2011 Jul;49(7):579-90
All:	2 reference(s)