Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gata4tm3.1Wtp
Name:	GATA binding protein 4; transgene insertion 3.1, William T Pu
MGI ID:	MGI:5308206
Synonyms:	CVDC/B2B program mutation, GATA4flbio
Gene:	Gata4  Location: Chr14:63436371-63509141 bp, - strand  Genetic Position: Chr14, 33.24 cM
Alliance:	Gata4tm3.1Wtp page

Germline Transmission:	Earliest citation of germline transmission: J:179371
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified
Project Collection:	B2B/CvDC

Allele Type:    Targeted Mutation:    Insertion   Mutation details: Flag and bio epitope tags and an FRT flanked neo cassette were inserted at the C terminus of the gene via homologous recombination. Flp mediated recombination removed the neo cassette. (J:179371)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gata4 Mutation:	36 strains or lines available

Original:	J:179371 He A, et al., PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42
All:	6 reference(s)