Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pomt2tm1.1Hhu
Name:	protein-O-mannosyltransferase 2; targeted mutation 1.1, Huaiyu Hu
MGI ID:	MGI:5302103
Gene:	Pomt2  Location: Chr12:87153635-87194742 bp, - strand  Genetic Position: Chr12, 41.3 cM
Alliance:	Pomt2tm1.1Hhu page

Germline Transmission:	Earliest citation of germline transmission: J:179356
Parent Cell Line:	D2 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6J)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed. (J:179356)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pomt2 Mutation:	38 strains or lines available

Original:	J:179356 Hu H, et al., Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. J Comp Neurol. 2011 May 1;519(7):1320-37
All:	2 reference(s)