Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-COP4*E123T*H134R,-tdTomato)Gfng
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Guoping Feng
MGI ID:	MGI:5301821
Synonyms:	R26-CAG-LSL-2XChETA-tdTomato, Rosa26-CAG-LSL-2XChETA-P2A-TdTomato-WPRE
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-COP4*E123T*H134R,-tdTomato)Gfng page

Germline Transmission:	Earliest citation of germline transmission: J:179349
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: A targeting vector, which contained the CAG promoter, a loxP site flanked STOP fragment and pGK-NEO-pA cassette, 2 copies of channelrhodopsin-2 with E123T mutation (ChETA variant) and the H134R mutation, P2A-tdTomato variant of Enhanced Red Fluorescent Protein, and WPRE (Woodchuck Hepatitis Virus (WHP) Posttranscriptional Regulatory Element) sequence to enhance expression level, was inserted into the locus. (J:179349)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:179349 Feng G, Direct Data Submission 2012/01/17. MGI Direct Data Submission. 2012;
All:	8 reference(s)