Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Elk3tm1(KOMP)Mbp
Name:	ELK3, member of ETS oncogene family; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:5299453
Gene:	Elk3  Location: Chr10:93083276-93146997 bp, - strand  Genetic Position: Chr10, 48.04 cM, cytoband C-D1
IMPC:	Elk3 gene page

Mutant Cell Lines:	DEPD00579_1_A03, DEPD00579_1_A04, DEPD00579_1_B01, DEPD00579_1_B03, DEPD00579_1_B04, DEPD00579_1_C01, DEPD00579_1_C02, DEPD00579_1_C03, DEPD00579_1_C04, DEPD00579_1_D01, DEPD00579_1_D02, DEPD00579_1_D03, DEPD00579_1_D04, DEPD00579_1_E01, DEPD00579_1_E02, DEPD00579_1_E04, DEPD00579_1_F02, DEPD00579_1_F03, DEPD00579_1_F04, DEPD00579_1_G04
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 340 starting at position 93120563 and ending at position 93120903 of Chromosome 10 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Elk3 Mutation:	19 strains or lines available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	1 reference(s)