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Gria4tm1Yfkk
Targeted Allele Detail
Summary
Symbol: Gria4tm1Yfkk
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4); targeted mutation 1, Yasuyuki Fukumaki
MGI ID: MGI:5298021
Gene: Gria4  Location: Chr9:4417896-4796234 bp, - strand  Genetic Position: Chr9, 2.46 cM
Alliance: Gria4tm1Yfkk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178206
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 12 was replaced with a neo cassette. Western blot analysis confirmed the absence of protein expression in the cerebrum and cerebellum. (J:178206)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gria4 Mutation:  72 strains or lines available
References
Original:  J:178206 Sagata N, et al., Comprehensive behavioural study of GluR4 knockout mice: implication in cognitive function. Genes Brain Behav. 2010 Nov;9(8):899-909
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory