Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pitx3tm1.1Jae
Name:	paired-like homeodomain transcription factor 3; targeted mutation 1.1, Rudolf Jaenisch
MGI ID:	MGI:5297588
Synonyms:	Pitx3-eGFP
Gene:	Pitx3  Location: Chr19:46124124-46136765 bp, - strand  Genetic Position: Chr19, 38.75 cM
Alliance:	Pitx3tm1.1Jae page

Germline Transmission:	Earliest citation of germline transmission: J:177859
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector containing a splice acceptor-eGFP-ires-pac-pA cassette and a floxed PGK-hygro cassette was used to replace exons 2, 3 and half of 4. Cre-mediated recombination excised the floxed hygro. (J:177859)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pitx3 Mutation:	22 strains or lines available

Original:	J:177859 Kim J, et al., Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell. 2011 Nov 4;9(5):413-9
All:	1 reference(s)