Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm3(RNAi:Fabp4)Mrl
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Merck Research Laboratory
MGI ID:	MGI:5295755
Synonyms:	shFABP4
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm3(RNAi:Fabp4)Mrl page

Germline Transmission:	Earliest citation of germline transmission: J:177476
Parent Cell Line:	ART4.12 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S6/SvEvTac)F1

Allele Type:    Targeted Mutation:    Insertion   Gt(ROSA)26Sortm3(RNAi:Fabp4)Mrl involves 1 genes/genome features (Fabp4) View all   Mutation details: RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte inserted a short hairpin RNA targeting Fabp4 into the locus. (J:177476)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:177476 Yang R, et al., RNAi-mediated germline knockdown of FABP4 increases body weight but does not improve the deranged nutrient metabolism of diet-induced obese mice. Int J Obes (Lond). 2011 Feb;35(2):217-25
All:	1 reference(s)