H2-D1b-tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
H2-D1b-tm1(KOMP)Mbp |
Name: |
histocompatibility 2, D region locus 1; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:5293871 |
Gene: |
H2-D1 Location: Chr17:35482070-35486473 bp, + strand Genetic Position: Chr17, 18.61 cM
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IMPC: |
H2-D1 gene page |
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Mutant Cell Lines: |
DEPD00573_4_B05, DEPD00573_4_B07, DEPD00573_4_B08, DEPD00573_4_C08, DEPD00573_4_D06, DEPD00573_4_D07, DEPD00573_4_E06, DEPD00573_4_E08, DEPD00573_4_F06, DEPD00573_4_F08, DEPD00573_4_G05, DEPD00573_4_G06, DEPD00573_4_G08, DEPD00573_4_H05, DEPD00573_4_H06, DEPD00573_4_H07 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 3622 starting at position 35482305 and ending at position 35485927 of Chromosome 17 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any H2-D1 Mutation: |
45 strains or lines available
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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