Slc13a5tm1.1Helf
Targeted Allele Detail
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Symbol: |
Slc13a5tm1.1Helf |
Name: |
solute carrier family 13 (sodium-dependent citrate transporter), member 5; targeted mutation 1.1, Stephen L Helfand |
MGI ID: |
MGI:5293234 |
Synonyms: |
SLC13A5floxed |
Gene: |
Slc13a5 Location: Chr11:72132815-72158048 bp, - strand Genetic Position: Chr11, 43.95 cM
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Alliance: |
Slc13a5tm1.1Helf page
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Germline Transmission: |
Earliest citation of germline transmission:
J:176732
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Parent Cell Line: |
Other (see notes) (ES Cell)
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Strain of Origin: |
(129S/SvEv x C57BL/6)F1
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 1 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette, leaving exons 1 - 6 floxed.
(J:176732)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc13a5 Mutation: |
35 strains or lines available
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D2 ES cells were used (J:176732)
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Original: |
J:176732 Birkenfeld AL, et al., Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab. 2011 Aug 3;14(2):184-95 |
All: |
2 reference(s) |
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