Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Irx3tm2Hui
Name:	Iroquois related homeobox 3; targeted mutation 2, Chi-chung Hui
MGI ID:	MGI:5292474
Synonyms:	Irx33myc-6his
Gene:	Irx3  Location: Chr8:92525139-92528282 bp, - strand  Genetic Position: Chr8, 44.55 cM
Alliance:	Irx3tm2Hui page

Germline Transmission:	Earliest citation of germline transmission: J:175992
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted Mutation:    Insertion   Mutation details: Three myc-tags and 6 histidines were inserted at the C terminus and an inverted HSV-neo cassette was inserted 3' to the gene via homologous recombination. (J:175992)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Irx3 Mutation:	24 strains or lines available

Original:	J:175992 Zhang SS, et al., Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13576-81
All:	2 reference(s)