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Ptpmt1tm1.1Jedi
Targeted Allele Detail
Summary
Symbol: Ptpmt1tm1.1Jedi
Name: protein tyrosine phosphatase, mitochondrial 1; targeted mutation 1.1, Jack E Dixon
MGI ID: MGI:5291923
Synonyms: Ptpmt1floxed
Gene: Ptpmt1  Location: Chr2:90741057-90748395 bp, - strand  Genetic Position: Chr2, 50.44 cM, cytoband E1
Alliance: Ptpmt1tm1.1Jedi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176087
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. The neo cassette as deleted by flp recombinase. (J:176087)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptpmt1 Mutation:  12 strains or lines available
References
Original:  J:176087 Zhang J, et al., Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 8;13(6):690-700
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory