Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax3tm6.2Buck
Name:	paired box 3; targeted mutation 6.2, Margaret E Buckingham
MGI ID:	MGI:5291823
Synonyms:	Pax3EGFP8
Gene:	Pax3  Location: Chr1:78077904-78173771 bp, - strand  Genetic Position: Chr1, 39.79 cM
Alliance:	Pax3tm6.2Buck page

Germline Transmission:	Earliest citation of germline transmission: J:176192
Parent Cell Line:	CK35 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: Flp-mediated recombination removed the puro cassette, loxP site, Pax8 cDNA, and IRES-nlacZ. A single loxP site, EGFP gene, and FRT site remain in intron 1. (J:176192)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax3 Mutation:	50 strains or lines available

Original:	J:176192 Hayashi S, et al., Lack of In Vivo Functional Compensation Between Pax Family Groups II and III in Rodents. Mol Biol Evol. 2011 Oct;28(10):2787-98
All:	3 reference(s)