Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lmnb1tm1.1Sgy
Name:	lamin B1; targeted mutation 1.1, Stephen G Young
MGI ID:	MGI:5285669
Synonyms:	Lmnb1fl
Gene:	Lmnb1  Location: Chr18:56840885-56886496 bp, + strand  Genetic Position: Chr18, 30.84 cM
Alliance:	Lmnb1tm1.1Sgy page

Germline Transmission:	Earliest citation of germline transmission: J:174963
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT-flanked beta-geo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. (J:174963)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

20 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lmnb1 Mutation:	38 strains or lines available

Original:	J:174963 Yang SH, et al., An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. Hum Mol Genet. 2011 Sep 15;20(18):3537-44
All:	8 reference(s)