Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Mouse Clinical Institute
MGI ID:	MGI:5285396
Synonyms:	ROSA26FLPo-YFP
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics page

Germline Transmission:	Earliest citation of germline transmission: J:185484
Parent Cell Line:	BD10 (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note chicken CAG   Mutation details: A construct, which contains a beta actin promoter and CMV enchancer driving ubiquitous expression of flpo and EGFP separated by a 2a peptide sequence, was inserted into the locus. (J:185484)

Generation of the Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics allele

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:185484 Birling MC, et al., Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background. Genesis. 2012 Jun;50(6):482-9
All:	18 reference(s)