About   Help   FAQ
Sema5btm1.1Alk
Targeted Allele Detail
Summary
Symbol: Sema5btm1.1Alk
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B; targeted mutation 1.1, Alex L Kolodkin
MGI ID: MGI:5284882
Synonyms: Sema5Bflox
Gene: Sema5b  Location: Chr16:35361517-35485103 bp, + strand  Genetic Position: Chr16, 25.37 cM
Alliance: Sema5btm1.1Alk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174679
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and an FRT flanked neo cassette were inserted 5' of exon 2 and a second loxP site were inserted 3' of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:174679)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema5b Mutation:  80 strains or lines available
References
Original:  J:174679 Matsuoka RL, et al., Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron. 2011 Aug 11;71(3):460-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory