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Sema5atm1.1Alk
Targeted Allele Detail
Summary
Symbol: Sema5atm1.1Alk
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; targeted mutation 1.1, Alex L Kolodkin
MGI ID: MGI:5284880
Synonyms: Sema5Aflox
Gene: Sema5a  Location: Chr15:32244959-32696487 bp, + strand  Genetic Position: Chr15, 13.02 cM
Alliance: Sema5atm1.1Alk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174679
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted 5' of exon 6 and an FRT flanked inverted neo cassette and second loxP site were inserted 3' of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:174679)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema5a Mutation:  65 strains or lines available
References
Original:  J:174679 Matsuoka RL, et al., Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron. 2011 Aug 11;71(3):460-73
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory