Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ppargtm1.2Mgn
Name:	peroxisome proliferator activated receptor gamma; targeted mutation 1.2, Mark A Magnuson
MGI ID:	MGI:2385457
Synonyms:	PPARgammadel
Gene:	Pparg  Location: Chr6:115337912-115467360 bp, + strand  Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
Alliance:	Ppargtm1.2Mgn page

Germline Transmission:	Earliest citation of germline transmission: J:75120
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination of Ppargtm1Mgn resulted in the excision of the floxed region containing both exon 2 and the neo cassette. A single loxP site was left in between exons 1 and 3. (J:75120)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pparg Mutation:	39 strains or lines available

Original:	J:75120 Jones JR, et al., Generation and functional confirmation of a conditional null PPARgamma allele in mice. Genesis. 2002 Feb;32(2):134-7
All:	1 reference(s)