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Targeted Allele Detail
Symbol: Ppargtm1.1Mgn
Name: peroxisome proliferator activated receptor gamma; targeted mutation 1.1, Mark A Magnuson
MGI ID: MGI:2385456
Synonyms: PPARgammaflox, PPARgammalox
Gene: Pparg  Location: Chr6:115360951-115490399 bp, + strand  Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
Germline Transmission:  Earliest citation of germline transmission: J:75120
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
Mutation detailsPartial cre mediated recombination of Ppargtm1Mgn resulted in the excision of the neo cassette in intron 2. Single loxP sites remained in introns 1 and 2, flanking exon 2. (J:75120)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pparg Mutation:  29 strains or lines available
Original:  J:75120 Jones JR, et al., Generation and functional confirmation of a conditional null PPARgamma allele in mice. Genesis. 2002 Feb;32(2):134-7
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory