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Mdm2tm1Snj
Targeted Allele Detail
Summary
Symbol: Mdm2tm1Snj
Name: transformed mouse 3T3 cell double minute 2; targeted mutation 1, Steven N Jones
MGI ID: MGI:2385452
Synonyms: Mdm2SJcnd1
Gene: Mdm2  Location: Chr10:117524780-117546663 bp, - strand  Genetic Position: Chr10, 66.32 cM, cytoband C1-C3
Alliance: Mdm2tm1Snj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75119
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed region containing exons 11 and 12 and a neo cassette 560 base pairs downstream of the polyA signal was inserted at the endogenous locus via homologous recombination. (J:75119)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mdm2 Mutation:  54 strains or lines available
References
Original:  J:75119 Steinman HA, et al., Generation of an Mdm2 conditional allele in mice. Genesis. 2002 Feb;32(2):142-4
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory