Mdm2tm2.2Glo
Targeted Allele Detail
|
|
| Symbol: |
Mdm2tm2.2Glo |
| Name: |
transformed mouse 3T3 cell double minute 2; targeted mutation 2.2, Guillermina Lozano |
| MGI ID: |
MGI:2385442 |
| Synonyms: |
delta exons5/6-neo |
| Gene: |
Mdm2 Location: Chr10:117524780-117546663 bp, - strand Genetic Position: Chr10, 66.32 cM, cytoband C1-C3
|
| Alliance: |
Mdm2tm2.2Glo page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:75118
|
| Parent Cell Line: |
AB1 (ES Cell)
|
| Strain of Origin: |
129S7/SvEvBrd-Hprt1+
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutation: |
|
Disruption caused by insertion of vector
|
| |
|
Mutation details: The expression of Cre recombinase in the germline resulted in the excision of the floxed region containing exons 5 and 6, leaving the floxed neo cassette in intron 6 intact.
(J:75118)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Mdm2 Mutation: |
54 strains or lines available
|
|
| Original: |
J:75118 Grier JD, et al., Conditional allele of mdm2 which encodes a p53 inhibitor. Genesis. 2002 Feb;32(2):145-7 |
| All: |
1 reference(s) |
|
Analysis Tools
