Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ets1vs
Name:	E26 avian leukemia oncogene 1, 5' domain; variable spotting
MGI ID:	MGI:1856643
Gene:	Ets1  Location: Chr9:32547517-32669116 bp, + strand  Genetic Position: Chr9, 17.97 cM
Alliance:	Ets1vs page

Strain of Origin:

C3HeB/FeJ

Allele Type:    Spontaneous (Not Specified) Mutation:    Single point mutation   Mutation details: The molecular lesion is a nucleotide G-to-A transition in exon 3 at nucleotide position 647 (or coding nucleotide 305) (RefSeq NM_011808.2), which results in a glycine to glutamate substitution at residue 102 (p.G102E) within the Pointed (PNT) domain of the encoded protein. Multiple sequence alignment showed that this glycine residue is highly conserved among different species. (J:226957) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ets1 Mutation:	25 strains or lines available

Original:	J:14217 Spencer CA, et al., Variable spotting (vs). Mouse News Lett. 1988;81:71
All:	2 reference(s)