Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pth1rtm2Hmk
Name:	parathyroid hormone 1 receptor; targeted mutation 2, Henry M Kronenberg
MGI ID:	MGI:2183512
Synonyms:	Pprfl
Gene:	Pth1r  Location: Chr9:110551153-110576213 bp, - strand  Genetic Position: Chr9, 60.56 cM, cytoband F
Alliance:	Pth1rtm2Hmk page

Germline Transmission:	Earliest citation of germline transmission: J:77683
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 1 was flanked by an upstream neo cassette containing a 3' loxP site and another loxP site in intron 1. (J:77683)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pth1r Mutation:	28 strains or lines available

Original:	J:77683 Kobayashi T, et al., PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development. 2002 Jun;129(12):2977-86
All:	29 reference(s)