Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Egr2tm3.1Pch
Name:	early growth response 2; targeted mutation 3.1, Patrick Charnay
MGI ID:	MGI:2183228
Synonyms:	Krox20delta
Gene:	Egr2  Location: Chr10:67371305-67378018 bp, + strand  Genetic Position: Chr10, 34.96 cM, cytoband B5
Alliance:	Egr2tm3.1Pch page

Germline Transmission:	Earliest citation of germline transmission: J:75128
Parent Cell Line:	CK35 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Egr2tm3Pch in which exon 2 and flanking sequences were deleted by Cre mediated recombination. Mice carrying the Egr2tm3Pch allele were mated to Tg(Pgk1-cre)1Lni mice and offspring were screened for the heritable deletion. Immunohistochemistry experiments on homozygous embryos demonstrated that no detectable protein was encoded by this allele. (J:75128)

In Mice Carrying this Mutation:

2 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egr2 Mutation:	31 strains or lines available

Original:	J:75128 Taillebourg E, et al., Conditional, floxed allele of the Krox20 gene. Genesis. 2002 Feb;32(2):112-3
All:	1 reference(s)