Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tfap2ctm1Will
Name:	transcription factor AP-2, gamma; targeted mutation 1, Trevor Williams
MGI ID:	MGI:2182570
Synonyms:	Tcfap2c-
Gene:	Tfap2c  Location: Chr2:172391513-172400542 bp, + strand  Genetic Position: Chr2, 94.87 cM, cytoband H3-H4
Alliance:	Tfap2ctm1Will page

Germline Transmission:	Earliest citation of germline transmission: J:76369
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 300 bp region of the gene, including the 5' portion of exon 7 encoding the DNA binding domain, was replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were identified by PCR genotyping at 7.5 dpc. (J:76369)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfap2c Mutation:	28 strains or lines available

Original:	J:76369 Auman HJ, et al., Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development. 2002 Jun;129(11):2733-47
All:	3 reference(s)