Usf2tm1Msw
Targeted Allele Detail
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Symbol: |
Usf2tm1Msw |
Name: |
upstream transcription factor 2; targeted mutation 1, Michele Sawadogo |
MGI ID: |
MGI:2181680 |
Synonyms: |
Usf2(-) |
Gene: |
Usf2 Location: Chr7:30644673-30656228 bp, - strand Genetic Position: Chr7, 19.27 cM, cytoband A2-B1
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Alliance: |
Usf2tm1Msw page
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Germline Transmission: |
Earliest citation of germline transmission:
J:46788
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Parent Cell Line: |
AB1 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1+
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: 11 kb of the gene, including most of the 5' untranslated region and all of the coding exons, was deleted and replaced with a PGK-neo cassette via homologous recombination. The absence of gene expression in homozygous mutants was confirmed by electrophoretic mobility shift assay (EMSA) and Western blot analysis of nuclear extracts from mutant mouse embryonic fibroblasts (MEF).
(J:46788)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Usf2 Mutation: |
12 strains or lines available
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Original: |
J:46788 Sirito M, et al., Overlapping roles and asymmetrical cross-regulation of the USF proteins in mice. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3758-63 |
All: |
6 reference(s) |
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