Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Nr5a1tm2.1Klp
Name:	nuclear receptor subfamily 5, group A, member 1; targeted mutation 2.1, Keith L Parker
MGI ID:	MGI:2180092
Synonyms:	R
Gene:	Nr5a1  Location: Chr2:38582668-38604554 bp, - strand  Genetic Position: Chr2, 24.42 cM
Alliance:	Nr5a1tm2.1Klp page

Germline Transmission:	Earliest citation of germline transmission: J:66593
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This heritable allele is a derivative of Nr5a1tm2Klp in which the loxP-flanked sequences were deleted by ectopic Cre recombinase activity in germ cells. (J:66593)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

15 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr5a1 Mutation:	30 strains or lines available

Original:	J:66593 Zhao L, et al., Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development. 2001 Jan;128(2):147-54
All:	2 reference(s)