Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prphtm1Jpj
Name:	peripherin; targeted mutation 1, Jean-Pierre Julien
MGI ID:	MGI:2180052
Gene:	Prph  Location: Chr15:98953055-98956859 bp, + strand  Genetic Position: Chr15, 55.72 cM, cytoband E-F
Alliance:	Prphtm1Jpj page

Germline Transmission:	Earliest citation of germline transmission: J:76218
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: Exon 1 of this gene was disrupted by insertion of an nls-lacZ-neo cassette via homologous recombination. Northern and Western blot analyses confirmed the absence of gene expression in homozygous mutant animals. (J:76218)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prph Mutation:	21 strains or lines available

Original:	J:76218 Lariviere RC, et al., Reduced number of unmyelinated sensory axons in peripherin null mice. J Neurochem. 2002 May;81(3):525-32
All:	5 reference(s)