Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Cd24atm1Pjln
Name:	CD24a antigen; targeted mutation 1, P J Nielsen
MGI ID:	MGI:2179996
Synonyms:	CD24-, HSA-
Gene:	Cd24a  Location: Chr10:43454433-43460261 bp, + strand  Genetic Position: Chr10, 23.01 cM
Alliance:	Cd24atm1Pjln page

Germline Transmission:	Earliest citation of germline transmission: J:76695
Parent Cell Line:	N1 (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The promoter region and exon 1 were replaced with a neo cassette via homologous recombination. Gene transcripts were absent in spleen from homozygous mutant animals as determined by Northern blot analysis. (J:76695, J:76970)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

List all tumor models in MMHCdb carrying Cd24atm1Pjln

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd24a Mutation:	15 strains or lines available

Original:	J:76695 Nielsen PJ, et al., Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood. 1997 Feb 1;89(3):1058-67
All:	36 reference(s)