Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Neurog3tm2(tTA)Ggu
Name:	neurogenin 3; targeted mutation 2, Guoqiang Gu
MGI ID:	MGI:3850054
Synonyms:	Neurog3tTA
Gene:	Neurog3  Location: Chr10:61968869-61970542 bp, + strand  Genetic Position: Chr10, 32.35 cM, cytoband B4
Alliance:	Neurog3tm2(tTA)Ggu page

Germline Transmission:	Earliest citation of germline transmission: J:150074
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout, Transactivator) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding region was replaced with an IRES, tetracycline-controlled transactivator gene (tTA), polyadenylation signal, and frt-flanked puromycin resistance cassette. (J:150074)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neurog3 Mutation:	18 strains or lines available

Original:	J:150074 Wang S, et al., Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9715-20
All:	6 reference(s)