Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Chi3l1tm1Eli
Name:	chitinase 3 like 1; targeted mutation 1, Jack A Elias
MGI ID:	MGI:3846187
Synonyms:	BRP-39-, BRP39-, Chi3l1-
Gene:	Chi3l1  Location: Chr1:134109894-134117769 bp, + strand  Genetic Position: Chr1, 58.15 cM
Alliance:	Chi3l1tm1Eli page

Germline Transmission:	Earliest citation of germline transmission: J:148490
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 1-6 and part of the promoter were replaced with a floxed neomycin cassette. Gene inactivation was confirmed by immunoblot analysis of lung extracts. (J:148490)

Generation of the Chi3l1tm1Eli allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chi3l1 Mutation:	26 strains or lines available

Original:	J:148490 Lee CG, et al., Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 2009 May 11;206(5):1149-66
All:	19 reference(s)