About   Help   FAQ
Ifnar2m1Btlr
Chemically induced Allele Detail
Summary
Symbol: Ifnar2m1Btlr
Name: interferon (alpha and beta) receptor 2; mutation 1, Bruce Beutler
MGI ID: MGI:3841008
Synonyms: macro-2
Gene: Ifnar2  Location: Chr16:91169671-91202477 bp, + strand  Genetic Position: Chr16, 52.82 cM
Alliance: Ifnar2m1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis mutation was identified in an ex vivo screen of macrophages from G3 progeny of ENU mutagenized male mice for their ability to control viral infection. It comprises an A to T transition in the second of nine exons, which is the first coding exon of the gene, converting the methionine/translation initiation codon at nucleotide position 221 of the cDNA sequence to a codon specifying valine. (J:147329)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ifnar2 Mutation:  42 strains or lines available
References
Original:  J:147329 Won S, et al., Record for "macro-2", updated April 14th, 2009. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory