Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zap70m2Btlr
Name:	zeta-chain (TCR) associated protein kinase; mutation 2, Bruce Beutler
MGI ID:	MGI:5141315
Synonyms:	trebia
Gene:	Zap70  Location: Chr1:36800879-36821899 bp, + strand  Genetic Position: Chr1, 15.41 cM, cytoband A4-C1
Alliance:	Zap70m2Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced A to T transversion at position 1566 (NCBI RefSeq: NM_009539). The mutation results in a tyrosine to phenylalanine substitution at amino acid 492 (Y492F). (J:174837)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zap70 Mutation:	55 strains or lines available

Original:	J:174837 Beutler B, Direct Data Submission. MGI Direct Data Submission. 2011;v
All:	1 reference(s)