Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ulk2tm1.1Thsn
Name:	unc-51 like kinase 2; targeted mutation 1.1, Craig B Thompson
MGI ID:	MGI:5141011
Gene:	Ulk2  Location: Chr11:61666475-61745899 bp, - strand  Genetic Position: Chr11, 37.96 cM
Alliance:	Ulk2tm1.1Thsn page

Germline Transmission:	Earliest citation of germline transmission: J:174297
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed exons 1 through 3 and the neo cassette. (J:174297)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

87 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ulk2 Mutation:	58 strains or lines available

Original:	J:174297 Cheong H, et al., Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11121-6
All:	7 reference(s)