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Tbx1tm7.1Bld
Targeted Allele Detail
Summary
Symbol: Tbx1tm7.1Bld
Name: T-box 1; targeted mutation 7.1, Antonio Baldini
MGI ID: MGI:5140345
Synonyms: Tbx1deltaFox
Gene: Tbx1  Location: Chr16:18399729-18409412 bp, - strand  Genetic Position: Chr16, Syntenic
Alliance: Tbx1tm7.1Bld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166754
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe Fox binding site #1 was replaced with a floxed Hprt selection cassette. Cre-mediated recombination removed the selection cassette. (J:166754)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:  34 strains or lines available
References
Original:  J:166754 Zhang Z, et al., Manipulation of endogenous regulatory elements and transgenic analyses of the Tbx1 gene. Mamm Genome. 2010 Dec;21(11-12):556-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory