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Tg(Pdx1-cre/Esr1*)1Mga
Transgene Detail
Summary
Symbol: Tg(Pdx1-cre/Esr1*)1Mga
Name: transgene insertion 1, Maureen A Gannon
MGI ID: MGI:3839433
Synonyms: Pdx1AI-III-Cre/ERT, pdx1PBCreERTM, Tg(Pdx1-cre/ERT)1Mga
Transgene: Tg(Pdx1-cre/Esr1*)1Mga  Location: unknown  
Alliance: Tg(Pdx1-cre/Esr1*)1Mga page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pdx1-cre/Esr1*)1Mga expression driven by 1 gene
 
Mutation detailsThe 1 kb islet enhancer was used to drive inducible islet-specific expression of a cre/Esr1 fusion. Three lines were created with line 1 exhibiting the strongest expression. (J:99581)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdx1 (species not specified)
Summary of all recombinase alleles driven by Pdx1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Tg(Pdx1-cre/Esr1*)1Mga
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:99581 Zhang H, et al., Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase. Genesis. 2005 Jul;42(3):210-7
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory