Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hprt1tm3(APOA5)Lap
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Len A Pennacchio
MGI ID:	MGI:3839280
Synonyms:	APOA5*4
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm3(APOA5)Lap page

Germline Transmission:	Earliest citation of germline transmission: J:145098
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Hprt1tm3(APOA5)Lap expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human APOA5 (116519) Apoa5  (MGI:1913363)     Haplotype 4 of the human gene was knocked into the 5' untranslated region of the locus. (J:145098)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:145098 Ahituv N, et al., In vivo characterization of human APOA5 haplotypes. Genomics. 2007 Dec;90(6):674-9
All:	1 reference(s)