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Tfcp2tm1e(KOMP)Mbp
Targeted Allele Detail
Nomenclature
Symbol: Tfcp2tm1e(KOMP)Mbp
Name: transcription factor CP2; targeted mutation 1e, Mouse Biology Program, UCDavis
MGI ID: MGI:5007951
Gene: Tfcp2  Location: Chr15:100395893-100449889 bp, - strand  Genetic Position: Chr15, 56.33 cM
Mutation
origin
Mutant Cell Lines:  DEPD00560_2_A01, DEPD00560_2_A03, DEPD00560_2_A04, DEPD00560_2_B02, DEPD00560_2_C01, DEPD00560_2_C02, DEPD00560_2_D02, DEPD00560_2_D03, DEPD00560_2_E01, DEPD00560_2_E03, DEPD00560_2_E04, DEPD00560_2_F02, DEPD00560_2_F03, DEPD00560_2_F04, DEPD00560_2_G03, DEPD00560_2_H02
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 100420847 of Chromosome 15 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Tfcp2 Mutation:  16 strains or lines available
References
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory