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Bdnftm1Tes
Targeted Allele Detail
Summary
Symbol: Bdnftm1Tes
Name: brain derived neurotrophic factor; targeted mutation 1, Lino Tessarollo
MGI ID: MGI:3836988
Gene: Bdnf  Location: Chr2:109505045-109557352 bp, + strand  Genetic Position: Chr2, 56.63 cM
Alliance: Bdnftm1Tes page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146179
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
 
Mutation detailsExon 5 was replaced with one which contains an HA-tag. A floxed and frt-flanked neo cassette with a splice acceptor, similar to the in BayGenomics gene trap vectors, was inserted upstream of the modified exon 5. (J:146179)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bdnf Mutation:  38 strains or lines available
References
Original:  J:146179 Yang J, et al., Neuronal release of proBDNF. Nat Neurosci. 2009 Feb;12(2):113-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory