Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Roratm1(cre)Ddmo
Name:	RAR-related orphan receptor alpha; targeted mutation 1, Dennis D M O'Leary
MGI ID:	MGI:5000017
Synonyms:	RORalphaCre
Gene:	Rora  Location: Chr9:68561068-69295528 bp, + strand  Genetic Position: Chr9, 37.45 cM
Alliance:	Roratm1(cre)Ddmo page

Germline Transmission:	Earliest citation of germline transmission: J:171771
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Roratm1(cre)Ddmo expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Rora (MGI:104661)   Mutation details: An IRES/cre/FRT/neo/FRT expression cassette was inserted into the 3' noncoding region of the Rora gene. Cre expression is similar to endogenous expression. (J:171771, J:199176)

Activity:	Tissue activity of this recombinase allele
Driver:	Rora (mouse) Summary of all recombinase alleles driven by Rora. Alliance mouse Rora gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rora Mutation:	41 strains or lines available

Original:	J:171771 Wu CS, et al., Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706
All:	23 reference(s)